HYDERABAD: Advanced technology may have helped vaccine makers reduce the time to develop Covid-19 vaccines from 5 years to 350 days, but there is an urgent need to reduce timelines to under 100 days by ingestion formula 1 Approach to Vaccine Development, Dr Richard HatchettCEO, Coalition for Epidemic Preparedness Innovations (CEPI), said here on Thursday.
dr Hatchett gave a plenary address on the first day of BioAsia 2023 and pointed out that just as with Formula 1 racing, the pit stop time for race cars has been reduced by 97% from around a minute in 1950 to just 2 seconds in 2021 Vaccine development process can be significantly accelerated.

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Advocating a collaborative “One Health” approach to accelerating vaccine development to combat future pandemics, he said: “CEPI envisions the world working together to achieve dynamic preparedness before the next disease threatens to overwhelm us.”
“We need to be able to develop vaccines within 100 days if we want to stop a pandemic. To do this, we need a paradigm shift and focus on significant systematic investments in preparedness by creating a vaccine library and solving problems of vaccine development for different virus families,” he said.
“We also need to focus on operational excellence. When a new virus emerges, we need to be able to start preparations for new vaccines from day one. We need to be able to start clinical trials by day 30. We need to be able to complete combined phase 1 and phase 2 studies within 60 days (day 90),” he explained.
Here he pointed out that CEPI, with the support of G7 and G20 leaders, has already begun a “100-day mission to prepare the world to accelerate vaccine development timelines and end pandemics forever.”
As part of this, CEPI proposed the development of a global library of prototype vaccines that would serve as templates for developing new vaccines should a new virus emerge.
“There are approximately 270 viruses known to cause disease in humans. All are from 25-27 virus families. For some virus families like smallpox, we have the smallpox vaccine that protects against all known smallpox viruses, which was also used during the monkeypox outbreak,” said Dr. Hatchett.
“We don’t know when or where the next disease X will break out, but we do know it’s coming sooner or later, and we can be sure that at some point there will be closer interactions between animals, birds and humans that we will get to grips with.” have to get used to as we learn to live with this new era of infectious diseases and epidemics linked to climate change,” said Dr Hatchett.

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